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减肥和肥胖相关的疾病,从中国大陆患者3年结果腹腔镜袖状胃切除术的效果

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发表于 2016-9-28 08:24:59 | 显示全部楼层 |阅读模式

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减肥和肥胖相关的疾病,从中国大陆患者3年结果腹腔镜袖状胃切除术的效果
Effectiveness of laparoscopic sleeve gastrectomy for weight loss and obesity-associated co-morbidities- a 3-year outcome from Mainland Chinese patients

Abstract
BACKGROUND:
Laparoscopic sleeve gastrectomy (LSG) is becoming a stand-alone bariatric surgery for obesity, but its effectiveness for Mainland Chinese patients remains unclear.
摘要
背景
腹腔镜袖状胃切除术(LSG)成为肥胖的一个独立的减肥手术,但其对于中国内地的疗效尚不清楚。

OBJECTIVES:
To evaluate the effectiveness and safety of LSG for Mainland Chinese patients SETTING: A tertiary hospital METHODS: Retrospective analysis of patients admitted for LSG between January 2011 and February 2012 was performed. Medium-term outcome measures were: total weight loss (%TWL), excess weight loss (%EWL), co-morbidities, improvement, and complications.
目标:
评价的有效性和安全性,为中国大陆患者LSG设置:方法:三级医院住院LSG 2011年一月至2012年二月之间的患者进行回顾性分析。中期指标:总重量损失(% TWL),多余的重量损失(%EWL),并发症,改善和并发症。

RESULTS:
Seventy patients (body mass index [BMI] 40.8±5.9 kg/m2) underwent LSG, comprising 40 women and 30 men. The most common co-morbidity was diabetes (n = 29, 41.4%). Lost to follow-up rate for weight loss was 15.7%, 31.4%, and 41% at 1, 2, and 3 years. The %TWL was 34.4±6.1, 34.7±6.2 and 33.7±7.1 at 1, 2, and 3 years. The %EWL increased to 77.1±13.0, 77.9±12.2 and 77.2±13.1 at 1, 2, and 3years. The proportions of patients having successful weight loss were 100% or 85% at 3 years according the definition of %TWL>10% or %EWL>50%. Approximately 79.3%, 51.7%, and 44.8% of patients completed follow-up for glycemic control at each time point, respectively. The proportions of patients with optimal glycemic control (fasting blood glucose [FBG]<5.6 mmol/L; hemoglobin A1C [HbA1C]<6.5%) were 47.9%, 60.0%, and 69.2% at 1, 2, and 3years. The weight loss and glycemic control effect may be greater in the high BMI group (≥40 kg/m2). Early and late complications occurred in 8.6% and 7.1% of patients during follow-up.
结果:
七十例患者(体重指数[BMI] 40.8±5.9 kg/m2)接受整笔拨款,包括40名女性和30名男性。最常见的共同发病率为糖尿病组(n = 29,41.4%)。失去了后续的减肥率分别为15.7%,31.4%和1,41%,2,和3年。%±TWL 34.4 6.1,34.7 6.2和33.7±±7.1在1,2,和3年。±%EWL增加到77.1 13,77.9 12.2和77.2 13.1±±在1、2、3年。有成功减肥的患者比例分别为100%、85% 3年根据% TWL > 10%或%EWL > 50%的定义。大约79.3%,51.7%,和44.8%的患者在每一个时间点完成了随访,血糖控制。最佳的血糖控制的患者比例(空腹血糖FBG ] [<5.6 mmol/L;糖化血红蛋白HbA1c ] [ < 6.5%)分别为47.9%、60%、1和69.2%、2、3年。减肥和控制血糖的效果可以在高BMI组更大(≥40公斤/平方米)。8.6%和7.1%的患者在随访过程中发生的早期和晚期并发症。

CONCLUSIONS:
LSG is effective in weight loss and glycemic control and is safe for Mainland Chinese obese patients, especially for patients with a BMI≥40 kg/m2.
结论:
LSG是体重和血糖控制的有效和安全的中国内地肥胖患者,特别是BMI 40 kg/m2≥。

KEYWORDS:
Mainland Chinese patients; laparoscopic sleeve gastrectomy; obesity
关键词:
中国大陆患者;腹腔镜胃袖状切除术;肥胖

原文:
Effectiveness of laparoscopic sleeve gastrectomy for weight loss and obesity-ass.pdf (640.93 KB, 下载次数: 0, 售价: 99 香叶)
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