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[病历讨论] 骨结合

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发表于 2020-1-12 00:00:08 | 显示全部楼层 |阅读模式

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骨结合是指骨在植入物表面和植入物结构中的愈合潜力。 骨科和牙科植入物行业中使用的三维多孔可植入材料具有向内生长和向内生长[1] [2] [3]或骨结合的潜力。

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与骨整合的比较
常规的带纹理或涂层的植入物表面设计用于实现骨骼与植入物之间的接触,这称为向内生长。[4] Per-Ingvar Brnemark将这种长骨现象即骨整合定义为“有序的活骨与承重植入物表面之间的直接结构和功能连接。” [5]对于牙科植入物,它们骨整合。[6] ] [7] [8] [9] [10] [11]多孔可植入材料的设计目的是使骨骼不仅可以在材料上生长,还可以在其孔中生长,并且在某些情况下可以在材料的结构内相互连接。[7] [8] [9] [10] [11 ]

并发症
在某些情况下,患者的牙周缺损(受损或不良的骨骼结构)会阻碍骨整合。在骨骼与牙齿植入物骨整合之前,可能需要引导组织和/或骨骼再生。在这种情况下,可能需要结合屏障膜,骨钉和补充自体骨,以促进适当的骨整合。此外,已经对种植体表面修饰进行了研究并已整合,从而促进了最佳的组织-种植体界面(即骨整合,种植体-牙龈密封)[12] [13] [14]

参考
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Unger, AS. "Evaluation of a porous tantalum uncemented actetabular cup in revision total hip arthoplasty. Clinical and radiological 结果 of 60 hips". J Arthroplasty, 2005, p 1002-1009
Cohen R. "A porous tantalum trabedcular metal: basic science". Am J Orthrop, 2002, p. 216-217
Bobyn JD. "UHMWPE: the good, bad, & ugly. Fixation and bearing surfaces for the next millennium". Orthop, 1999, p. 810-812
Branemark PI. "Introduction to osseointegration". In Branemark PI, Zarb GA, and Albrektsson T. eds.: Tissue-Integrated Prosthese. Osseointegration in Clinical Dentistry. Chicago, IL: Quintessence Publishing Co, Inc.: 1985, p. 11-76
Branemark PI. "Introduction to osseointegration". In Branemark PI, Zarb GA, and Albrektsson T. eds.: Tissue-Integrated Prosthese. Osseointegration in Clinical Dentistry. Chicago, IL: Quintessence Publishing Co, Inc.: 1985, p. 11-76
Osseointegration Study, Journal of Oral Implantology, 2001—Burton E. Balkin et al.
Unger, AS. "Evaluation of a porous tantalum uncemented actetabular cup in revision total hip arthoplasty. Clinical and radiological 结果 of 60 hips". J Arthroplasty, 2005, p 1002-1009
Cohen R. "A porous tantalum trabedcular metal: basic science". Am J Orthrop, 2002, p. 216-217
Bobyn JD. "UHMWPE: the good, bad, & ugly. Fixation and bearing surfaces for the next millennium". Orthop, 1999, p. 810-812
Tsao AK. "Biomechanical and clinical evaluations of a porous tantaluym implant for the treatment of early-stage osteonecrosis". J Bone Joint Surg, 2005, p.22-27
Bobyn JD. "Clinical validation of a structural porous tantalum biomaterial for adult reconstruction". J Bone Joint Surg, 2004, p. 123-129
E.T. den Braber, H.V. Jansen, M.J. de Boer, H.J.E. Croes, M. Elwenspoek, and J.A. Jansen, Scanning electron microscopic, transmission electron microscopic, and confocal laser scanning microscopic observation of fibroblasts cultured on microgrooved surfaces of bulk titanium substrata, J. Biomed. Mater. Res., 1998, 425-433
S. Raghavendra, M. C. Wood, T. D. Taylor. Early wound healing adjacent to endosseous dental implants: A review of the literature. Int. J. Oral Maxillofac. Implants., 2005, 425–31
F. Rupp, L. Scheideler, N. Olshanska, M. de Wild, M. Wieland, J. Geis-Gerstorfer. Enhancing surface free energy and hydrophilicity through chemical modification of micro结构d titanium implant surfaces. J. Biomed. Mater. Res. A. 2006, 323–33 4
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