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| 对血流动力学变化、利多卡因和艾司洛尔输注镇痛要求的影响，和在腹腔镜胆囊切除术手术恢复 Effects of lidocaine and esmolol infusions on hemodynamic changes, analgesic requirement, and recovery in laparoscopic cholecystectomy operations Abstract OBJECTIVE: We compared the effects of lidocaine and esmolol infusions on intraoperative hemodynamic changes, intraoperative and postoperative analgesic requirements, and recovery in laparoscopic cholecystectomy surgery. 摘要 目的： 我们比较了利多卡因注射艾司洛尔对术中血流动力学变化的影响，术中及术后镇痛的要求，并在腹腔镜胆囊切除手术的恢复。 METHODS: The first group (n=30) received IV lidocaine infusions at a rate of 1.5mg/kg/min and the second group (n=30) received IV esmolol infusions at a rate of 1mg/kg/min. Hemodynamic changes, intraoperative and postoperative analgesic requirements, and recovery characteristics were evaluated. 方法: 第一组（n = 30）静脉注射利多卡因注射率在1.5mg/kg/min和第二组（n = 30）的速度在1mg／kg／min静脉注射艾司洛尔Hemodynamic改变输注，术中及术后镇痛的要求，和恢复特性的评价。 RESULTS: In the lidocaine group, systolic arterial blood pressures values were lower after the induction of anesthesia and at 20min following surgical incision (p<0.05). Awakening time was shorter in the esmolol group (p<0.001); Ramsay Sedation Scale scores at 10min after extubation were lower in the esmolol group (p<0.05). The modified Aldrete scores at all measurement time points during the recovery period were relatively lower in the lidocaine group (p<0.05). The time to attain a modified Aldrete score of ≥9 points was prolonged in the lidocaine group (p<0.01). Postoperative resting and dynamic VAS scores were higher in the lidocaine group at 10 and 20min after extubation (p<0.05, p<0.01, respectively). Analgesic supplements were less frequently required in the lidocaine group (p<0.01). 结果: 在利多卡因组，收缩期动脉血压值均较低，麻醉诱导后，在20min后手术切口（P＜0.05）。在艾司洛尔组苏醒时间较短（P＜0.001）；拉姆齐镇静评分在拔管后10min均低于艾司洛尔组（P＜0.05）。在利多卡因组改良Aldrete评分在所有测量的时间点恢复时期相对较低（P＜0.05）。时间来达到改良Aldrete评分达到9分≥利多卡因组明显延长（P＜0.01）。术后静息和动态VAS评分均高于利多卡因组在10和20min后拔管（P＜0.05，P＜0.01，分别）。利多卡因组不需要止痛药（P＜0.01）。 CONCLUSION: In laparoscopic cholecystectomies, lidocaine infusion had superiorities over esmolol infusions regarding the suppression of responses to tracheal extubation and postoperative need for additional analgesic agents in the long run, while esmolol was more advantageous with respect to rapid recovery from anesthesia, attenuation of early postoperative pain, and modified Aldrete recovery (MAR) scores and time to reach MAR score of 9 points. 结论： 腹腔镜胆囊切除术，利多卡因有优势超过艾司洛尔输注有关反应的抑制气管拔管和长期术后需要额外的镇痛剂，而艾司洛尔更有利的相对于从麻醉恢复快，术后早期疼痛的衰减，恢复和改良Aldrete（损坏）分数和时间达到损坏的9分评分。 KEYWORDS: Colecistectomia laparoscópica; Esmolol; Laparoscopic cholecystectomy; Lidocaina; Lidocaine; Recovery; Recuperação 关键词： 腹腔镜胆囊切除术；腹腔镜胆囊切除术；利多卡因；艾司洛尔；利多卡因；回收；回收率；  原文：http://www.dxye.com/thread-24298-1-1.html |
